At Sunstone Therapies, we believe healing goes deeper than the surface. While traditional oncology focuses on physical treatments, many patients still struggle with the psychological and emotional challenges of cancer. Our mission is to address the whole patient, which is why we created the 2Dose Study. This clinical trial, led by Dr. Manish Agrawal, builds on our initial study where 80% of participants experienced a greater than 50% reduction in depressive symptoms. The 2Dose Study will explore whether psilocybin is more effective than an active placebo and if two doses are better than one. The trial is open to people with all stages of cancer, not just advanced disease.
A new paper published in Psychedelic Medicine introduces a novel model combining Meaning-Centered Psychotherapy (MCP) with psilocybin-assisted therapy (PAT) for patients with advanced cancer and depression. Developed from Sunstone Therapies’ investigator-initiated trial, the approach—called MCP-PSIL—aims to help patients reduce distress and find deeper meaning while navigating serious illness.
In psychedelic therapy clinical research, setting clear expectations is paramount. Transparent communication about potential disappointments can significantly reduce anxiety and foster a more grounded, trusting, and ultimately, healing journey for participants.
Co-founder and CEO, Dr. Manish Agrawal, recently shared his expertise and vision for the future of psychedelic-assisted therapy in oncology in a four-part interview series with Pharmacy Times’ Lead Editor, Alana Hippensteele.
Sunstone is pleased to begin enrollment of two clinical studies exploring the therapeutic potential of DMT (N,N-dimethyltryptamine) and its analogs.
June 16, 2025 | A new study conducted by Sunstone Therapies suggests that a single dose of psilocybin, combined with psychological support, can provide sustained relief from depression for some cancer patients.
Manish Agrawal, MD, Co-Founder and CEO of Sunstone Therapies Manish Agrawal, MD, brings an extensive academic, clinical, and research background […]
Kimberly Roddy, MBA, Co-Founder and COO of Sunstone Therapies Kimberly Roddy is the Co-Founder and Chief Operations Officer of Sunstone […]
Psychedelic therapy can helps patients face difficult emotions with curiosity, supporting deep healing and lasting change.
Sunstone Therapies Co-Founders Dr. Manish Agrawal and Kim Roddy spoke with Psychedelic Alpha’s Editor, Josh Hardman, about the challenges and insights they’ve gained after delivering hundred of psychedelic therapy sessions.
Psychedelic Medicine–History and Clinical Research January 30, 2025 Psychedelic Medicine: History and Clinical Research explores the resurgence of psychedelics in […]
Manish Agrawal, MD joins Living Medicine host, Dr. Sandra Newes to discuss the challenges and future of psychedelic-assisted therapy research.
Manish Agrawal, MD joins Power to the Patient host Brandon Li to discuss the transformative role of psychedelics in cancer care and mental health.
Psychedelic-assisted therapies may be a promising treatment for combat related moral injury.
October 22, 2024 Sunstone Therapies is pleased to announce that Dr. Manish Agrawal was appointed by Maryland Governor Wes Moore […]
Psychedelic-assisted therapies bring a critical new dimension to questions about subjectivity in psychiatry.
Psychedelic-assisted therapies bring a critical new dimension to questions about subjectivity in psychiatry.
Dear Sunstone Community, It has been a pivotal couple of weeks for the field of psychedelic-assisted therapy (PAT) following the […]
Psychedelic-assisted therapies bring a critical new dimension to questions about subjectivity in psychiatry.
Dr. Manish Agrawal speaks PATs ability to treat not just the physical manifestations of cancer but also the mental and emotional toll it takes on patients.
Enhanced therapist training standards are necessary, along with an additional PAT therapists.
Learn about psychedelic therapy in this WebMD article that unpacks MOAs of psychedelic medicines & their potential in mental health treatment.
Explore the healing powers of psychedelics in ‘How to Change Your Mind’—a 4-part series based on Michael Pollan’s book.
Realizing the promise of psychedelic-assisted therapy
How psychedelic-assisted therapy might help patients and their loved ones.
Learn about the crucial role therapists play in psychedelic therapy & their impact on treatment outcomes.
Sunstone Therapies announces publication of positive data on use of Psilocybin Therapy for patients with cancer and major depression disorder
Sunstone Therapies announces publication of positive data on use of Psilocybin Therapy for patients with cancer and major depression disorder
Sunstone Therapies announces publication of positive data on use of Psilocybin Therapy for patients with cancer and major depression disorder
Sunstone Therapies presents data at ASCO showing positive long-term follow-up results from psilocybin therapy in cancer patients with major depressive disorder (MDD)
Sunstone Therapies announces publication of positive data on use of Psilocybin Therapy for patients with cancer and major depression disorder
Sit down with Roland Griffiths and his wife to learn how a stage IV cancer diagnosis has changed their lives.
Psychedelics are unlocking new ways to treat conditions like addiction and depression.
September 12, 2022 | Recognizing the limitations of conventional oncology in addressing end-of-life psychological distress, Dr. Manish Agrawal and his team at Sunstone Therapies are advancing research into psilocybin-assisted therapy for patients with advanced cancer. In a recent clinical trial, a single psilocybin dose combined with group therapy resulted in a clinically significant reduction in depression symptoms for 80% of participants—highlighting the potential of psychedelic-assisted interventions to enhance quality of life and psychological well-being in palliative care settings.